This article reviews the political reform to decentralization in Chile that will begin to rule in full after the regional governors’ elections of 2021. Based on an intergovernmental relations approach, I show possible scenarios of lack of coordination in regional political dynamics that could lead to conflicts as a result of the existence of two new regional authorities with similar powers. In view of the weakness of the new institutional design, this article proposes the creation of a regional policy coordination body. The main conclusion is that the decentralization reform was conceived more as a process of autonomy and democratization, than as an instance of strengthening intergovernmental relations in order to implement better subnational public policies.